RDG006026 This area of NMRI research has also included the development of telemetering and microcalorimetry devices used in the nations manned space flight program, radiation tolerance studies relating to the manning of nuclear ships, and studies of oxygen requirements and toxicity having application of submarine operations. In this photograph, a volunteer test subject is briefed prior to entering one of the Institutes deep isolation laboratories. These facilities are used in seeking answers to the problems facing small groups working under isolated conditions, and the studies relate directly to prolonged submerged submarine cruises.